https://github.com/antipax/node-bones

Here's a nice little application skeleton for Node.js 0.6.x that I whipped up in preparation for a hackathon at Group Commerce.  Twitter Bootstrap, Jade, Express, CoffeeScript and LESS are included, along with all the boilerplate you'd usually have to write. Automatic asset compilation is all set up and you've got a nice little configuration file which is just CoffeeScript. It's also ready for deployment on Heroku.

Hope you find it useful!